Cartilage tissue engineering identifies abnormal human induced pluripotent stem cells

Safety is the foremost issue in all human cell therapies, but human induced pluripotent stem cells (iPSCs) currently lack a useful safety indicator. Studies in chimeric mice have demonstrated that certain lines of iPSCs are tumorigenic; however a similar screen has not been developed for human iPSCs...

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Bibliographic Details
Main Authors: Yamashita, Akihiro, Liu, Shiying, Woltjen, Knut, Thomas, Bradley, Meng, Guoliang, Hotta, Akitsu, Takahashi, Kazutoshi, Ellis, James, Yamanaka, Shinya, Rancourt, Derrick E.
Format: Online
Language:English
Published: Nature Publishing Group 2013
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3680803/