Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma

Overexpression of SSAT by DENSPM treatment induces cell detachment and apoptosis in glioblastoma

N1,N11-diethylnorspermine (DENSPM), a polyamine analog that induces expression of spermidine/spermine N1-acetyltransferase (SSAT) and reduces polyamine levels in eukaryotic cells, has demonstrated anticancer effects in many cancer cell types. Gene expression of SSAT after treatment with DENSPM was m...

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Bibliographic Details
Main Authors: TIAN, YE, WANG, SHIZHAO, WANG, BIN, ZHANG, JIANNING, JIANG, RONGCAI, ZHANG, WEI
Format: Online
Language:English
Published: D.A. Spandidos 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583519/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3583519/

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