Vorinostat approved in Japan for treatment of cutaneous T-cell lymphomas: status and prospects
Histone acetylation and deacetylation play important roles in the regulation of gene transcription and in the modulation of chromatin structure. The levels of histone acetylation are determined by the activities of histone acetyltransferases and histone deacetylases (HDACs). HDACs are associated wit...
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| Format: | Online |
| Language: | English |
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Dove Medical Press
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346061/ |