Successful Shortening of Tuberculosis Treatment Using Adjuvant Host-Directed Therapy with FDA-Approved Phosphodiesterase Inhibitors in the Mouse Model

Global control of tuberculosis (TB), an infectious disease that claims nearly 2 million lives annually, is hindered by the long duration of chemotherapy required for curative treatment. Lack of adherence to this intense treatment regimen leads to poor patient outcomes, development of new or addition...

Full description

Bibliographic Details
Main Authors: Maiga, Mamoudou, Agarwal, Nisheeth, Ammerman, Nicole C., Gupta, Radhika, Guo, Haidan, Maiga, Marama C., Lun, Shichun, Bishai, William R.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3272040/