Estrogen Augments Shear Stress–Induced Signaling and Gene Expression in Osteoblast-like Cells via Estrogen Receptor–Mediated Expression of β1-Integrin

Estrogen and mechanical forces are positive regulators for osteoblast proliferation and bone formation. We investigated the synergistic effect of estrogen and flow-induced shear stress on signal transduction and gene expression in human osetoblast-like MG63 cells and primary osteoblasts (HOBs) using...

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Bibliographic Details
Main Authors: Yeh, Chiuan-Ren, Chiu, Jeng-Jiann, Lee, Chih-I, Lee, Pei-Ling, Shih, Yu-Tsung, Sun, Jui-Sheng, Chien, Shu, Cheng, Cheng-Kung
Format: Online
Language:English
Published: Wiley Subscription Services, Inc., A Wiley Company 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3153398/