Severe hypoxia induces chemo-resistance in clinical cervical tumors through MVP over-expression

Severe hypoxia induces chemo-resistance in clinical cervical tumors through MVP over-expression

Oxygen molecule modulates tumour response to radiotherapy. Higher radiation doses are required under hypoxic conditions to induce cell death. Hypoxia may inhibit the non-homologous end-joining DNA repair through down regulating Ku70/80 expression. Hypoxia induces drug resistance in clinical tumours,...

Full description

Bibliographic Details
Main Authors: Lara, Pedro C, Lloret, Marta, Clavo, Bernardino, Apolinario, Rosa M, Henríquez-Hernández, Luis Alberto, Bordón, Elisa, Fontes, Fausto, Rey, Agustín
Format: Online
Language:English
Published: BioMed Central 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2728103/

Similar Items

Similar Items