A randomised trial of low-dose/high-frequency chemotherapy as palliative treatment of poor-prognosis small-cell lung cancer: a Cancer research Campaign trial.

We report the results of a randomised trial in extensive small-cell lung cancer (SCLC) of a novel approach to palliative chemotherapy. A widely used 3 weekly regimen was compared with the same drugs given at half the dose but twice the frequency with the same intended overall dose intensity (DI). A...

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Bibliographic Details
Main Authors: James, L. E., Gower, N. H., Rudd, R. M., Spiro, S. G., Harper, P. G., Trask, C. W., Partridge, M., Ruiz de Elvira, M. C., Souhami, R. L.
Format: Online
Language:English
Published: Nature Publishing Group 1996
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2074560/