E2F1 activation is responsible for pituitary adenomas induced by HMGA2 gene overexpression

The High Mobility Group protein HMGA2 is a nuclear architectural factor that plays a critical role in a wide range of biological processes including regulation of gene expression, embryogenesis and neoplastic transformation. Several studies are trying to identify the mechanisms by which HMGA2 protei...

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Bibliographic Details
Main Authors: Fedele, Monica, Pierantoni, Giovanna Maria, Visone, Rosa, Fusco, Alfredo
Format: Online
Language:English
Published: BioMed Central 2006
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563461/