The human glutathione S-transferase supergene family, its polymorphism, and its effects on susceptibility to lung cancer.
Cytosolic glutathione S-transferases (GSTs) are a supergene family of dimeric enzymes capable of detoxifying a number of carcinogenic electrophiles. Of the numerous components of tobacco smoke, the polycyclic aromatic hydrocarbons appear to be the principal compounds that yield substrates for these...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
1992
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1519626/ |