Signalling pathway involved in nitric oxide synthase type II activation in chondrocytes: synergistic effect of leptin with interleukin-1
The objective of the present study was to investigate the effect of leptin, alone or in combination with IL-1, on nitric oxide synthase (NOS) type II activity in vitro in human primary chondrocytes, in the mouse chondrogenic ATDC5 cell line, and in mature and hypertrophic ATDC5 differentiated chondr...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2005
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1174950/ |