Different genome stability proteins underpin primed and naïve adaptation in E. coli CRISPR-Cas immunity
CRISPR-Cas is a prokaryotic immune system built from capture and integration of invader DNA into CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) loci, termed ‘Adaptation’, which is dependent on Cas1 and Cas2 proteins. In Escherichia coli, Cascade-Cas3 degrades invader DNA to effec...
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Oxford University Press
2015
|
| Online Access: | http://eprints.nottingham.ac.uk/31310/ http://eprints.nottingham.ac.uk/31310/ http://eprints.nottingham.ac.uk/31310/ http://eprints.nottingham.ac.uk/31310/1/Ivancic-Bace%20et%20al%20CRISPR%202015%20NAR.pdf |