Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases

Assessment of intratumor immune-microenvironment in colorectal cancers with extranodal extension of nodal metastases

Abstract Background No data is available on the molecular background of the extra-nodal extension (ENE) of lymph node metastasis (LN) in colorectal cancer (CRC). Methods A series of 22 ENE-positive CRCs was considered and three samples per case were selected (the primary CRC, an ENE-negative and an...

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Main Authors: Matteo Fassan, Luca Vianello, Diana Sacchi, Giuseppe N. Fanelli, Giada Munari, Marco Scarpa, Rocco Cappellesso, Fotios Loupakis, Cristiano Lanza, Roberta Salmaso, Claudia Mescoli, Nicola Valeri, Marco Agostini, Edoardo D’Angelo, Sara Lonardi, Salvatore Pucciarelli, Nicola Veronese, Claudio Luchini, Massimo Rugge
Format: Article
Language:English
Published: BioMed Central 2018-09-01
Series:Cancer Cell International
Subjects:
Extranodal extension
Metastasis
Colorectal cancer
Biomarkers
Online Access:http://link.springer.com/article/10.1186/s12935-018-0634-8

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http://link.springer.com/article/10.1186/s12935-018-0634-8

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