Simultaneous determination of primaquine and carboxyprimaquine in plasma using solid phase extraction and LC-MS assay
Sensitive bioanalytical methods are required for pharmacokinetic studies in children, due to the small volume and modest number of samples that can be obtained. We sought to develop a LC–MS assay for primaquine and its active metabolite, carboxyprimaquine, following simultaneous, solid phase extract...
| Main Authors: | , , , , |
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| Format: | Journal Article |
| Published: |
Elsevier
2012
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| Subjects: | |
| Online Access: | http://hdl.handle.net/20.500.11937/40766 |