Expression of the PlA2 allele of glycoprotein IIIa and its impact on platelet function

by Floyd, Christopher N, Ferro, Albert, Warner, Timothy D
Published 2015

Thrombosis Is Reduced by Inhibition of COX-1, but Unaffected by Inhibition of COX-2, in an Acute Model of Platelet Activation in the Mouse

by Armstrong, Paul C., Kirkby, Nicholas S., Zain, Zetty N., Emerson, Michael, Mitchell, Jane A., Warner, Timothy D.
Published 2011

Drug-Free Platelets Can Act as Seeds for Aggregate Formation During Antiplatelet Therapy

by Hoefer, Thomas, Armstrong, Paul C., Finsterbusch, Michaela, Chan, Melissa V., Kirkby, Nicholas S., Warner, Timothy D.
Published 2015

Pregnane X receptor regulates drug metabolism and transport in the vasculature and protects from oxidative stress

by Swales, Karen E., Moore, Rick, Truss, Nicola J., Tucker, Arthur, Warner, Timothy D., Negishi, Masahiko, Bishop-Bailey, David
Published 2012

COX-2 Protects against Atherosclerosis Independently of Local Vascular Prostacyclin: Identification of COX-2 Associated Pathways Implicate Rgl1 and Lymphocyte Networks

by Kirkby, Nicholas S., Lundberg, Martina H., Wright, William R., Warner, Timothy D., Paul-Clark, Mark J., Mitchell, Jane A.
Published 2014

Aspirin inhibits the production of proangiogenic 15(S)-HETE by platelet cyclooxygenase-1

by Rauzi, Francesca, Kirkby, Nicholas S., Edin, Matthew L., Whiteford, James, Zeldin, Darryl C., Mitchell, Jane A., Warner, Timothy D.
Published 2016

Differential COX-2 induction by viral and bacterial PAMPs: Consequences for cytokine and interferon responses and implications for anti-viral COX-2 directed therapies☆

by Kirkby, Nicholas S., Zaiss, Anne K., Wright, William R., Jiao, Jing, Chan, Melissa V., Warner, Timothy D., R. Herschman, Harvey, Mitchell, Jane A.
Published 2013

Aspirin-triggered 15-epi-lipoxin A4 predicts cyclooxygenase-2 in the lungs of LPS-treated mice but not in the circulation: implications for a clinical test

by Kirkby, Nicholas S., Chan, Melissa V., Lundberg, Martina H., Massey, Karen A., Edmands, William M. B., MacKenzie, Louise S., Holmes, Elaine, Nicolaou, Anna, Warner, Timothy D., Mitchell, Jane A.
Published 2013

P2Y12 receptor blockade synergizes strongly with nitric oxide and prostacyclin to inhibit platelet activation

by Chan, Melissa V., Knowles, Rebecca B. M., Lundberg, Martina H., Tucker, Arthur T., Mohamed, Nura A., Kirkby, Nicholas S., Armstrong, Paul C. J., Mitchell, Jane A., Warner, Timothy D.
Published 2016

Endogenous Epoxygenases Are Modulators of Monocyte/Macrophage Activity

by Bystrom, Jonas, Wray, Jessica A., Sugden, Mary C., Holness, Mark J., Swales, Karen E., Warner, Timothy D., Edin, Matthew L., Zeldin, Darryl C., Gilroy, Derek W., Bishop-Bailey, David
Published 2011

LC-MS/MS Confirms That COX-1 Drives Vascular Prostacyclin Whilst Gene Expression Pattern Reveals Non-Vascular Sites of COX-2 Expression

by Kirkby, Nicholas S., Zaiss, Anne K., Urquhart, Paula, Jiao, Jing, Austin, Philip J., Al-Yamani, Malak, Lundberg, Martina H., MacKenzie, Louise S., Warner, Timothy D., Nicolaou, Anna, Herschman, Harvey R., Mitchell, Jane A.
Published 2013

Inherited human group IVA cytosolic phospholipase A2 deficiency abolishes platelet, endothelial, and leucocyte eicosanoid generation

by Kirkby, Nicholas S., Reed, Daniel M., Edin, Matthew L., Rauzi, Francesca, Mataragka, Stefania, Vojnovic, Ivana, Bishop-Bailey, David, Milne, Ginger L., Longhurst, Hilary, Zeldin, Darryl C., Mitchell, Jane A., Warner, Timothy D.
Published 2016

Evidence That Links Loss of Cyclooxygenase-2 With Increased Asymmetric Dimethylarginine: Novel Explanation of Cardiovascular Side Effects Associated With Anti-Inflammatory Drugs

by Ahmetaj-Shala, Blerina, Kirkby, Nicholas S., Knowles, Rebecca, Al’Yamani, Malak, Mazi, Sarah, Wang, Zhen, Tucker, Arthur T., Mackenzie, Louise, Armstrong, Paul C. J., Nüsing, Rolf M., Tomlinson, James A. P., Warner, Timothy D., Leiper, James, Mitchell, Jane A.
Published 2015

Protocol for a human in vivo model of acute cigarette smoke inhalation challenge in smokers with COPD: monitoring the nasal and systemic immune response using a network biology app...

by Ross, Clare L, Galloway-Phillipps, Neil, Armstrong, Paul C, Mitchell, Jane A, Warner, Timothy D, Brearley, Christopher, Ito, Mari, Tunstall, Tanushree, Elkin, Sarah, Kon, Onn Min, Hansel, Trevor T, Paul-Clark, Mark J
Published 2015

Human Platelets Utilize Cycloxygenase-1 to Generate Dioxolane A3, a Neutrophil-activating Eicosanoid*

by Hinz, Christine, Aldrovandi, Maceler, Uhlson, Charis, Marnett, Lawrence J., Longhurst, Hilary J., Warner, Timothy D., Alam, Saydul, Slatter, David A., Lauder, Sarah N., Allen-Redpath, Keith, Collins, Peter W., Murphy, Robert C., Thomas, Christopher P., O'Donnell, Valerie B.
Published 2016