Novel Combination of Impella and Extra Corporeal Membrane Oxygenation as a Bridge to Full Recovery in Fulminant Myocarditis

by Narain, Sachin, Paparcuri, Gian, Fuhrman, Thomas M., Silverman, Richard B., Peruzzi, William T.
Published 2012

Simplified 2-Aminoquinoline-Based Scaffold for Potent and Selective Neuronal Nitric Oxide Synthase Inhibition

by Cinelli, Maris A., Li, Huiying, Chreifi, Georges, Martásek, Pavel, Roman, Linda J., Poulos, Thomas L., Silverman, Richard B.
Published 2014

Nitric Oxide Synthase Inhibitors That Interact with Both Heme Propionate and Tetrahydrobiopterin Show High Isoform Selectivity

by Kang, Soosung, Tang, Wei, Li, Huiying, Chreifi, Georges, Martásek, Pavel, Roman, Linda J., Poulos, Thomas L., Silverman, Richard B.
Published 2014

Enzymatic and Cryoreduction EPR Studies of the Hydroxylation of Methylated Nω-Hydroxy-l-arginine Analogues by Nitric Oxide Synthase from Geobacillus stearothermophilus

by Davydov, Roman, Labby, Kristin Jansen, Chobot, Sarah E., Lukoyanov, Dmitriy A., Crane, Brian R., Silverman, Richard B., Hoffman, Brian M.
Published 2014

Novel 2,4-Disubstituted Pyrimidines as Potent, Selective, and Cell-Permeable Inhibitors of Neuronal Nitric Oxide Synthase

by Mukherjee, Paramita, Li, Huiying, Sevrioukova, Irina, Chreifi, Georges, Martásek, Pavel, Roman, Linda J., Poulos, Thomas L., Silverman, Richard B.
Published 2014

Mechanism of Inactivation of γ-Aminobutyric Acid Aminotransferase by (1S,3S)-3-Amino-4-difluoromethylene-1-cyclopentanoic Acid (CPP-115)

by Lee, Hyunbeom, Doud, Emma H., Wu, Rui, Sanishvili, Ruslan, Juncosa, Jose I., Liu, Dali, Kelleher, Neil L., Silverman, Richard B.
Published 2015

Potent and Selective Double-Headed Thiophene-2-carboximidamide Inhibitors of Neuronal Nitric Oxide Synthase for the Treatment of Melanoma

by Huang, He, Li, Huiying, Yang, Sun, Chreifi, Georges, Martásek, Pavel, Roman, Linda J., Meyskens, Frank L., Poulos, Thomas L., Silverman, Richard B.
Published 2014

The Mobility of a Conserved Tyrosine Residue Controls Isoform-Dependent Enzyme–Inhibitor Interactions in Nitric Oxide Synthases

by Li, Huiying, Jamal, Joumana, Delker, Silvia, Plaza, Carla, Ji, Haitao, Jing, Qing, Huang, He, Kang, Soosung, Silverman, Richard B., Poulos, Thomas L.
Published 2014

Proteasome Activation is a Mechanism for Pyrazolone Small Molecules Displaying Therapeutic Potential in Amyotrophic Lateral Sclerosis

by Trippier, Paul C., Zhao, Kevin Tianmeng, Fox, Susan G., Schiefer, Isaac T., Benmohamed, Radhia, Moran, Jason, Kirsch, Donald R., Morimoto, Richard I., Silverman, Richard B.
Published 2014

Structure-Based Design of Bacterial Nitric Oxide Synthase Inhibitors

by Holden, Jeffrey K., Kang, Soosung, Hollingsworth, Scott A., Li, Huiying, Lim, Nathan, Chen, Steven, Huang, He, Xue, Fengtian, Tang, Wei, Silverman, Richard B., Poulos, Thomas L.
Published 2014

The Sirtuin-2 Inhibitor AK7 Is Neuroprotective in Models of Parkinson’s Disease but Not Amyotrophic Lateral Sclerosis and Cerebral Ischemia

by Chen, Xiqun, Wales, Pauline, Quinti, Luisa, Zuo, Fuxing, Moniot, Sébastien, Herisson, Fanny, Rauf, Nazifa Abdul, Wang, Hua, Silverman, Richard B., Ayata, Cenk, Maxwell, Michelle M., Steegborn, Clemens, Schwarzschild, Michael A., Outeiro, Tiago F., Kazantsev, Aleksey G.
Published 2015

Regulation of aldosterone secretion by Cav1.3

by Xie, Catherine B., Haris Shaikh, Lalarukh, Garg, Sumedha, Tanriver, Gizem, Teo, Ada E. D., Zhou, Junhua, Maniero, Carmela, Zhao, Wanfeng, Kang, Soosung, Silverman, Richard B., Azizan, Elena A. B., Brown, Morris J.
Published 2016