Cell Stress Induces Upregulation of Osteopontin via the ERK Pathway in Type II Alveolar Epithelial Cells

by Kato, Aki, Okura, Takafumi, Hamada, Chizuru, Miyoshi, Seigo, Katayama, Hitoshi, Higaki, Jitsuo, Ito, Ryoji
Published 2014

A case of EGFR mutant lung adenocarcinoma that acquired resistance to EGFR-tyrosine kinase inhibitors with MET amplification and epithelial-to-mesenchymal transition

by Miyoshi, Seigo, Kato, Takahide, Katayama, Hitoshi, Ito, Ryoji, Mizuno, Yosuke, Okura, Takafumi, Higaki, Jitsuo
Published 2015

Combination therapy with sivelestat and recombinant human soluble thrombomodulin for ARDS and DIC patients

by Miyoshi, Seigo, Ito, Ryoji, Katayama, Hitoshi, Dote, Kentaro, Aibiki, Mayuki, Hamada, Hironobu, Okura, Takafumi, Higaki, Jitsuo
Published 2014

Antitumor activity of MEK and PI3K inhibitors against malignant pleural mesothelioma cells in vitro and in vivo

by MIYOSHI, SEIGO, HAMADA, HIRONOBU, HAMAGUCHI, NAOHIKO, KATO, AKI, KATAYAMA, HITOSHI, IRIFUNE, KAZUNORI, ITO, RYOJI, MIYAZAKI, TATSUHIKO, OKURA, TAKAFUMI, HIGAKI, JITSUO
Published 2012

Usefulness of a selective neutrophil elastase inhibitor, sivelestat, in acute lung injury patients with sepsis

by Miyoshi, Seigo, Hamada, Hironobu, Ito, Ryoji, Katayama, Hitoshi, Irifune, Kazunori, Suwaki, Toshimitsu, Nakanishi, Norihiko, Kanematsu, Takanori, Dote, Kentaro, Aibiki, Mayuki, Okura, Takafumi, Higaki, Jitsuo
Published 2013