MicroRNAs as Mediators of the Ageing Process

by Harries, Lorna W.
Published 2014

A rare SNP in pre-miR-34a is associated with increased levels of miR-34a in pancreatic beta cells

by Locke, Jonathan M., Lango Allen, Hana, Harries, Lorna W.
Published 2013

Permanent Neonatal Diabetes Caused by Creation of an Ectopic Splice Site within the INS Gene

by Garin, Intza, Perez de Nanclares, Guiomar, Gastaldo, Elena, Harries, Lorna W., Rubio-Cabezas, Oscar, Castaño, Luis
Published 2012

Oxidative Metabolism Genes Are Not Responsive to Oxidative Stress in Rodent Beta Cell Lines

by Morrison, Faer, Johnstone, Karen, Murray, Anna, Locke, Jonathan, Harries, Lorna W.
Published 2012

Changes in CEBPB expression in circulating leukocytes following eccentric elbow-flexion exercise

by Blackwell, Jamie, Harries, Lorna W., Pilling, Luke C., Ferrucci, Luigi, Jones, Andrew, Melzer, David
Published 2014

A cautionary tale: the non-causal association between type 2 diabetes risk SNP, rs7756992, and levels of non-coding RNA, CDKAL1-v1

by Locke, Jonathan M., Wei, Fan-Yan, Tomizawa, Kazuhito, Weedon, Michael N., Harries, Lorna W.
Published 2015

The splice site variant rs11078928 may be associated with a genotype-dependent alteration in expression of GSDMB transcripts

by Morrison, Faer S, Locke, Jonathan M, Wood, Andrew R, Tuke, Marcus, Pasko, Dorota, Murray, Anna, Frayling, Tim, Harries, Lorna W
Published 2013

A Role for SPARC in the Moderation of Human Insulin Secretion

by Harries, Lorna W., McCulloch, Laura J., Holley, Janet E., Rawling, Thomas J., Welters, Hannah J., Kos, Katarina
Published 2013

Role of microRNAs in the age-associated decline of pancreatic beta cell function in rat islets

by Tugay, Ksenia, Guay, Claudiane, Marques, Ana C., Allagnat, Florent, Locke, Jonathan M., Harries, Lorna W., Rutter, Guy A., Regazzi, Romano
Published 2015

Changes in the expression of splicing factor transcripts and variations in alternative splicing are associated with lifespan in mice and humans

by Lee, Benjamin P., Pilling, Luke C., Emond, Florence, Flurkey, Kevin, Harrison, David E., Yuan, Rong, Peters, Luanne L., Kuchel, George A., Ferrucci, Luigi, Melzer, David, Harries, Lorna W.
Published 2016

The PI3K regulatory subunit gene PIK3R1 is under direct control of androgens and repressed in prostate cancer cells

by Munkley, Jennifer, Livermore, Karen E., McClurg, Urszula L., Kalna, Gabriela, Knight, Bridget, McCullagh, Paul, McGrath, John, Crundwell, Malcolm, Leung, Hing Y., Robson, Craig N., Harries, Lorna W., Rajan, Prabhakar, Elliott, David J.
Published 2015

Glycosylation is an Androgen-Regulated Process Essential for Prostate Cancer Cell Viability☆

by Munkley, Jennifer, Vodak, Daniel, Livermore, Karen E., James, Katherine, Wilson, Brian T., Knight, Bridget, Mccullagh, Paul, Mcgrath, John, Crundwell, Malcolm, Harries, Lorna W., Leung, Hing Y., Robson, Craig N., Mills, Ian G., Rajan, Prabhakar, Elliott, David J.
Published 2016

Allelic heterogeneity and more detailed analyses of known loci explain additional phenotypic variation and reveal complex patterns of association

by Wood, Andrew R., Hernandez, Dena G., Nalls, Michael A., Yaghootkar, Hanieh, Gibbs, J. Raphael, Harries, Lorna W., Chong, Sean, Moore, Matthew, Weedon, Michael N., Guralnik, Jack M., Bandinelli, Stefania, Murray, Anna, Ferrucci, Luigi, Singleton, Andrew B, Melzer, David, Frayling, Timothy M.
Published 2011

Cross-tissue methylomic profiling strongly implicates a role for cortex-specific deregulation of ANK1 in Alzheimer’s disease neuropathology

by Lunnon, Katie, Smith, Rebecca, Hannon, Eilis, De Jager, Philip, Srivastava, Gyan, Volta, Manuela, Troakes, Claire, Al-Sarraj, Safa, Burrage, Joe, Macdonald, Ruby, Condliffe, Daniel, Harries, Lorna W., Katsel, Pavel, Haroutunian, Vahram, Kaminsky, Zachary, Joachim, Catharine, Powell, John, Lovestone, Simon, Bennett, David A., Schalkwyk, Leonard, Mill, Jonathan
Published 2014

The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer

by Munkley, Jennifer, Oltean, Sebastian, Vodák, Daniel, Wilson, Brian T., Livermore, Karen E., Zhou, Yan, Star, Eleanor, Floros, Vasileios I., Johannessen, Bjarne, Knight, Bridget, McCullagh, Paul, McGrath, John, Crundwell, Malcolm, Skotheim, Rolf I., Robson, Craig N., Leung, Hing Y., Harries, Lorna W., Rajan, Prabhakar, Mills, Ian G., Elliott, David J.
Published 2015

Human longevity is influenced by many genetic variants: evidence from 75,000 UK Biobank participants

by Pilling, Luke C., Atkins, Janice L., Bowman, Kirsty, Jones, Samuel E., Tyrrell, Jessica, Beaumont, Robin N., Ruth, Katherine S., Tuke, Marcus A., Yaghootkar, Hanieh, Wood, Andrew R., Freathy, Rachel M., Murray, Anna, Weedon, Michael N., Xue, Luting, Lunetta, Kathryn, Murabito, Joanne M., Harries, Lorna W., Robine, Jean-Marie, Brayne, Carol, Kuchel, George A., Ferrucci, Luigi, Frayling, Timothy M., Melzer, David
Published 2016

Peripheral Blood Transcriptomic Signatures of Fasting Glucose and Insulin Concentrations

by Chen, Brian H., Hivert, Marie-France, Peters, Marjolein J., Pilling, Luke C., Hogan, John D., Pham, Lisa M., Harries, Lorna W., Fox, Caroline S., Bandinelli, Stefania, Dehghan, Abbas, Hernandez, Dena G., Hofman, Albert, Hong, Jaeyoung, Joehanes, Roby, Johnson, Andrew D., Munson, Peter J., Rybin, Denis V., Singleton, Andrew B., Uitterlinden, André G., Ying, Saixia, Melzer, David, Levy, Daniel, van Meurs, Joyce B.J., Ferrucci, Luigi, Florez, Jose C., Dupuis, Josée, Meigs, James B., Kolaczyk, Eric D.
Published 2016